Eledoisin Related Peptide ( Eledoisin-Related Peptide; Eledoisin RP )

产品货号. M29877 CAS No. 2990-43-4

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HNMR

HPLC

MSDS

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产品名称

Eledoisin Related Peptide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Eledoisin Related Peptide is a tachykinin receptor ligand and analogue of substance P. ERP can increase spontaneous activity and depolarizing neurons by decreasing membrane conductance.
产品描述

Eledoisin Related Peptide is a tachykinin receptor ligand and analogue of substance P. ERP can increase spontaneous activity and depolarizing neurons by decreasing membrane conductance. (In Vivo):Eledoisin Related Peptide shares with Substance P (SP) a common N-terminal amino acid sequence and has been shown by to have SP-like activity in the periphery (gut and salivary glands) and the CNS. Eledoisin-related peptide seems to be roughly equipotent with Substance P at identical ejection currents on the single-cell activity of neurons in this nucleus. Both glutamate and substance P (and its analogue, eledoisin-related peptide) have excitatory effects on the activity of respiratory neurons and reflex interneurons.
同义词

Eledoisin-Related Peptide; Eledoisin RP
通路

GPCR/G Protein
靶点

Neurokinin Receptor
受体

Tachykinin receptor
研究领域

——
适应症

——

Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322.

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